Clinical Pharmacology

image - Clinical Pharmacology

The Department of Clinical Pharmacology and Toxicology (CPT), part of St Vincent's Clinical School, UNSW Medicine and St Vincent’s Hospital Sydney, was established by Professor Denis Wade in 1970.

The core activities of the CPT Department focus on promoting the safe and effective use of medicine as well as patient safety at St Vincent’s Hospital and in the community. This includes:

  • Inpatient service for the management and assessment of overdoses and poisoning,
  • Consulting on therapeutic problems,
  • Guidance on the usage of electronic medication management and decision support tools,
  • Research and teaching on medicines.

We provide leadership in the clinical pharmacology, toxicology, therapeutics and quality use of medicines locally, nationally and internationally through our research, teaching and training, advisory roles and collaborations.

We focus on understanding inter-subject variation in response to medicines through high quality clinical research.

Research Interests

Research is also a very large part of who we are and what we do.  We conduct ground-breaking research in many exciting areas. 
  • we are researching powerful techniques for individualising pharmacotherapy using pharmacokinetic/pharmacodynamic models
  • allopurinol used in gout, metformin used in diabetes and various antibiotics, anti-fungals and antiviral drugs are currently being studied 
  • investigating the mechanisms of paracetamol actions, examining genetic factors that predict serious adverse drug reactions and also explain variation in response to medicines, especially transporter molecules and their controlling genes
  • understanding how doctors choose what medicines to prescribe and why guidelines are not always followed
  • exploring new ways of assisting doctors in making the best decisions for their patients, including innovative strategies like electronic prescribing and computerised decision support.
Our ultimate goal is safe and effective therapy for patients.

Come and join us!

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